The authors also conduct a numerical study illustrating the relative properties of the conventional and subject-centered approach and provide an example. RESULTS: A simple-to-implement approach for estimating the subject-centered FROC curve and its overall index can be formulated as a type of stratified FROC analysis.
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This yields the empirical probability that an abnormal image rating exceeds that of a normal image and can be shown to be identical to the area under the trapezoidal ROC curve. Non-parametric FROC analysis is possible (18,19) along similar lines. One approach is to use the area under the raw FROC curve to the left of a specified value of the abscissa as the figure of merit.
A Free-response Receiver Operating Characteristic (FROC) study was carried out on radiographers to assess their performance. 19 experienced radiographers untrained in image interpretation were shown 30 wrist radiographs, 15 of which had distal radial fractures, 15 did not.
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Although the importance of a single index summarizing the entire curve over all decision thresholds is well recognized in ROC analysis (e.g., area under the ROC curve), currently there is no widely accepted summary of a system being evaluated under the FROC paradigm.
However, this does not mean than one FROC analysis method (e.g., JAFROC) is suitable for all or most research questions. JAFROC is a statistically viable approach, but it should only be used if it answers the research question. A future area for research is development of FROC-ROC analysis methods designed to answer specific research questions.
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